Joseph H Bisesi

Joseph H Bisesi,

Assistant Professor & PhD/MHS Direc

Department: HP-ENVIRONMENTAL GLOBAL HLTH
Business Phone: (352) 294-4703
Business Email: jbisesi@phhp.ufl.edu

About Joseph H Bisesi

Dr. Joseph Bisesi is an Assistant Professor of the Department of Environmental and Global Health and a member of the Center for Environmental and Human Toxicology and the Emerging Pathogens Institute at the University of Florida. He received his B.S. and M.S. in Biological Sciences, and his Ph.D. in Environmental Toxicology from Clemson University in 2005, 2007, and 2011, respectively. He then completed his post-doc at the University of Florida, where he studied molecular toxicology. Dr. Bisesi then joined the Department of Environmental and Global Health in 2014. In addition to his teaching and research program, Dr. Bisesi currently serves as the program director for Ph.D. and Masters programs.

Dr. Bisesi’s training is grounded in environmental toxicology with a focus on studying the effects of waterborne toxicants in humans and aquatic organisms. His dissertation research was focused on understanding the impacts of antidepressants on the brain biochemistry and feeding behavior of aquatic organisms. Additional training in the examination of molecular mechanisms of toxicants in mammalian and fish models allows Dr. Bisesi to work across human health toxicology and ecotoxicology to address complex public and environmental health issues related to environmental contaminants. Dr. Bisesi’s current research program is focused on elucidating the effects and toxic mechanisms of numerous emerging contaminates, including nanomaterials, plasticizers, and pharmaceuticals as well as legacy contaminants of concern including pesticides and heavy metals. Much of his research is focused on the gastrointestinal system, which is an understudied target of chemical contaminants. His research has been published in numerous high impact environmental journals including Environmental Science and Technology, Environmental Toxicology and Chemistry, and Environmental Science: Nano. His research has been funded by the National Science Foundation.

Dr. Bisesi current projects include: probing the contributions of phthalate plasticizers to the obesity epidemic using zebrafish as a model, examining the desorption behavior of pharmaceuticals and pesticides bound to carbon nanomaterials in fish gastrointestinal systems, and exploring the impacts of heavy metals to aquatic organisms under varying pulsed exposure and water quality conditions, and examining the presence and impacts of environmental toxicants in developing countries including Haiti and Zambia.

Accomplishments

Best Paper Award
2019 · Environmental Toxicology and Chemistry (Journal)
Presidential Citation for Exemplary Service
2018 · Society of Environmental Toxicology and Chemistry
Induction into the Delta Omega Public Health Honor Society
2017 · Delta Omega, Beta Upsilon Chapter
Deans Citation Award
2014 · University of Florida College of Public Health and Health Professions

Research Profile

Dr. Bisesi’s current research interests include examining the role of the gastrointestinal system and associated microbiome in physiological response to toxicants, understanding interactions between nanomaterials and organic chemical contaminants in biological systems, using zebrafish as a model in the study mechanisms of environmental obesogens, exploring the presence, effects, and treatment of air and waterborne toxicants in developing countries (Haiti and Zambia), and fish behavior as an indicator sub-lethal aquatic toxicity.

Publications

2021
Contributions of biomass/solid fuel burning to blood pressure modification in women: A systematic review and meta-analysis.
American journal of human biology : the official journal of the Human Biology Council. [DOI] 10.1002/ajhb.23586. [PMID] 33645874.
2021
Implications of Insecticide-Treated Mosquito Net Fishing in Lower Income Countries.
Environmental health perspectives. 129(1) [DOI] 10.1289/EHP7001. [PMID] 33417508.
2021
Influence of Water Resource Recovery Facility Effluents on the Presence of Selected Trace Organic Contaminants (TOrCs) in the Reedy River, South Carolina.
Bulletin of environmental contamination and toxicology. [DOI] 10.1007/s00128-021-03365-7. [PMID] 34652459.
2021
Microbiome analysis and predicted relative metabolomic turnover suggest bacterial heme and selenium metabolism are altered in the gastrointestinal system of zebrafish (Danio rerio) exposed to the organochlorine dieldrin.
Environmental pollution (Barking, Essex : 1987). 268(Pt B) [DOI] 10.1016/j.envpol.2020.115715. [PMID] 33069042.
2021
Nano-scale applications in aquaculture: Opportunities for improved production and disease control.
Journal of fish diseases. 44(4):359-370 [DOI] 10.1111/jfd.13332. [PMID] 33559228.
2021
Plastics in our water: Fish microbiomes at risk?
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 39 [DOI] 10.1016/j.cbd.2021.100834. [PMID] 33930774.
2021
Recent insights from comparative animal microbiomics.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 40 [DOI] 10.1016/j.cbd.2021.100880. [PMID] 34304147.
2021
Transcriptomic Analysis of the Differential Nephrotoxicity of Diverse Brominated Flame Retardants in Rat and Human Renal Cells.
International journal of molecular sciences. 22(18) [DOI] 10.3390/ijms221810044. [PMID] 34576211.
2021
Virtual Special Issue of the Fifth Biennial Meeting of the North American Society for Comparative Endocrinology (Sociedad Norteamericana de Endocrinología Comparada; Societé Nord-Americaine d’Endocrinologie Comparée).
General and comparative endocrinology. 308 [DOI] 10.1016/j.ygcen.2021.113770. [PMID] 33819475.
2020
Antineoplastic Agents: Environmental Prevalence and Adverse Outcomes in Aquatic Organisms.
Environmental toxicology and chemistry. 39(5):967-985 [DOI] 10.1002/etc.4687. [PMID] 32266737.
2020
Evaluation of Microbiome-Host Relationships in the Zebrafish Gastrointestinal System Reveals Adaptive Immunity Is a Target of Bis(2-ethylhexyl) Phthalate (DEHP) Exposure.
Environmental science & technology. 54(9):5719-5728 [DOI] 10.1021/acs.est.0c00628. [PMID] 32255618.
2020
Gastrointestinal dysbiosis following diethylhexyl phthalate exposure in zebrafish (Danio rerio): Altered microbial diversity, functionality, and network connectivity.
Environmental pollution (Barking, Essex : 1987). 265(Pt B) [DOI] 10.1016/j.envpol.2020.114496. [PMID] 32806437.
2020
Regulation of endocrine systems by the microbiome: Perspectives from comparative animal models.
General and comparative endocrinology. 292 [DOI] 10.1016/j.ygcen.2020.113437. [PMID] 32061639.
2019
Examining the responses of the zebrafish (Danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate.
Environmental pollution (Barking, Essex : 1987). 245:1086-1094 [DOI] 10.1016/j.envpol.2018.11.032. [PMID] 30682743.
2019
Guest editors’ introduction – Special issue of the fifth biennial meeting of the North American Society for Comparative Endocrinology (Sociedad Norteamericana de Endocrinología Comparada; Societé Nord-Americaine d’Endocrinologie Comparée).
General and comparative endocrinology. 283 [DOI] 10.1016/j.ygcen.2019.113222. [PMID] 31319062.
2019
Utilization of Near Infrared Fluorescence Imaging to Track and Quantify the Pulmonary Retention of Single-Walled Carbon Nanotubes in Mice.
NanoImpact. 14 [DOI] 10.1016/j.impact.2019.100167. [PMID] 32818159.
2018
The gut microbiome and aquatic toxicology: An emerging concept for environmental health.
Environmental toxicology and chemistry. 37(11):2758-2775 [DOI] 10.1002/etc.4249. [PMID] 30094867.
2018
Tissue-Based Mapping of the Fathead Minnow (Pimephales promelas) Transcriptome and Proteome.
Frontiers in endocrinology. 9 [DOI] 10.3389/fendo.2018.00611. [PMID] 30459712.
2017
Effect of natural organic matter on the photo-induced toxicity of titanium dioxide nanoparticles.
Environmental toxicology and chemistry. 36(6):1661-1666 [DOI] 10.1002/etc.3702. [PMID] 27925281.
2017
Influence of the Gastrointestinal Environment on the Bioavailability of Ethinyl Estradiol Sorbed to Single-Walled Carbon Nanotubes.
Environmental science & technology. 51(2):948-957 [DOI] 10.1021/acs.est.6b04728. [PMID] 27977933.
2017
Single-walled carbon nanotubes modulate pulmonary immune responses and increase pandemic influenza a virus titers in mice.
Virology journal. 14(1) [DOI] 10.1186/s12985-017-0909-z. [PMID] 29273069.
2016
Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:159-173 [DOI] 10.1016/j.cbd.2016.04.003. [PMID] 27156127.
2016
Effects of an antidepressant mixture on the brain serotonin and predation behavior of hybrid striped bass.
Environmental toxicology and chemistry. 35(4):938-45 [DOI] 10.1002/etc.3114. [PMID] 26076900.
2016
The effects of bupropion on hybrid striped bass brain chemistry and predatory behavior.
Environmental toxicology and chemistry. 35(8):2058-65 [DOI] 10.1002/etc.3350. [PMID] 26748934.
2015
Dynamism of Stimuli-Responsive Nanohybrids: Environmental Implications.
Nanomaterials (Basel, Switzerland). 5(2):1102-1123 [DOI] 10.3390/nano5021102. [PMID] 28347054.
2015
Examination of Single-Walled Carbon Nanotubes Uptake and Toxicity from Dietary Exposure: Tracking Movement and Impacts in the Gastrointestinal System.
Nanomaterials (Basel, Switzerland). 5(2):1066-1086 [DOI] 10.3390/nano5021066. [PMID] 28347052.
2015
Oral bioavailability and sex specific tissue partitioning of quantum dots in fathead minnows, Pimephales promelas
Environmental Science-Nano. 2(6):583-593 [DOI] 10.1039/C5EN00122F.
2014
Control of transcriptional repression of the vitellogenin receptor gene in largemouth bass (Micropterus salmoides) by select estrogen receptors isotypes.
Toxicological sciences : an official journal of the Society of Toxicology. 141(2):423-31 [DOI] 10.1093/toxsci/kfu145. [PMID] 25061109.
2014
Effects of the antidepressant venlafaxine on fish brain serotonin and predation behavior.
Aquatic toxicology (Amsterdam, Netherlands). 148:130-8 [DOI] 10.1016/j.aquatox.2013.12.033. [PMID] 24486880.
2014
Emergent Properties and Toxicological Considerations for Nanohybrid Materials in Aquatic Systems.
Nanomaterials (Basel, Switzerland). 4(2):372-407 [DOI] 10.3390/nano4020372. [PMID] 28344229.
2014
Fate of single walled carbon nanotubes in wetland ecosystems
Environmental Science-Nano. 1(6):574-583 [DOI] 10.1039/C4EN00063C.
2014
Reprint of: Effects of the antidepressant venlafaxine on fish brain serotonin and predation behavior.
Aquatic toxicology (Amsterdam, Netherlands). 151:88-96 [DOI] 10.1016/j.aquatox.2014.02.015. [PMID] 24679646.
2014
Single-walled carbon nanotubes increase pandemic influenza A H1N1 virus infectivity of lung epithelial cells.
Particle and fibre toxicology. 11 [DOI] 10.1186/s12989-014-0066-0. [PMID] 25497303.
2014
Tracking and Quantification of Single-Walled Carbon Nanotubes in Fish Using Near Infrared Fluorescence
. 48:1973-1983
2014
Tracking and quantification of single-walled carbon nanotubes in fish using near infrared fluorescence.
Environmental science & technology. 48(3):1973-83 [DOI] 10.1021/es4046023. [PMID] 24383993.
2009
Culture of Pacific White Shrimp Litopenaeus vannamei in a Mixed-Ion Solution
North American Journal of Aquaculture. 71(2):134-137 [DOI] 10.1577/A08-015.1.

Grants

Aug 2021 ACTIVE
Examining potential off target effects in native Florida largemouth bass from aquatic invasive plant management
Role: Principal Investigator
Funding: FL FISH AND WILDLIFE CONSERVATION COMM
Mar 2021 ACTIVE
Examining thyroid hormone synthesis feedback loops as xenobiotic target for brominated flame retardant metabolites
Role: Principal Investigator
Funding: NATL INST OF HLTH NIEHS
Jul 2020 ACTIVE
OR-DRPD-ROF2020: A humanized peroxisome proliferator activated receptor alpha (PPARa) zebrafish: A new transgenic model for obesogenic chemical screening
Role: Principal Investigator
Funding: UF RESEARCH
May 2020 ACTIVE
Development of a feline hyperthyroid cell line
Role: Co-Investigator
Funding: ROYAL CANIN USA, INC
Apr 2020 ACTIVE
National Drug Early Warning System Coordinating Center
Role: Project Manager
Funding: NATL INST OF HLTH NIDA
Jul 2019 – Mar 2021
Characterization of effects from episodic metal exposures: Evaluation of the Biotic Ligand for Episodic Exposures (BLEEM) to copper, zinc, and aluminum
Role: Principal Investigator
Funding: WINDWARD ENVIRONMENTAL via ELECTRIC POWER RES INST
Apr 2019 – Aug 2020
Mosquito Net Fishing in Zambia
Role: Principal Investigator
Funding: SYRACUSE UNIVERSITY
Jul 2016 – Mar 2021
Understanding how interaction of single-walled carbon nanotubes with biological interfaces in the gastrointestinal system may alter chemical bioavailability
Role: Principal Investigator
Funding: NATL SCIENCE FOU

Education

Doctor of Philosophy in Environmental Toxicology
2011 · Clemson University
Master of Science in Biological Sciences
2007 · Clemson University
Bachelor of Science in Biological Sciences
2005 · Clemson University

Teaching Profile

Courses Taught
2020-2021
PHC6304 Environmental Toxicology Applications in Public Health
2016-2017,2019-2021
PHC6947 Occupational Health Field Research Experience
2019-2021
HSC4507 Environmental Toxicology Applications in Public Health
2019-2021
PHC7980 Research for Doctoral Dissertation
2017-2021
PHC7979 Advanced Research
2015-2021
PHC6937 Special Topics in Public Health
2020
PHC6424 Environmental Policy and Risk Management in Public Health
2018-2020
PHC6722 Environmental and Global Health Research Methods Rotation
2016-2019
PHC6601 Seminar in Contemporary Public Health Issues
2013-2016,2018-2019
PHC6313 Environmental Health Concepts in Public Health
2018-2019
HSC4970 Public Health and Health Professions Senior Honors Thesis
2017-2018
HSC4930 Special Topics
2018
ANG7980 Research for Doctoral Dissertation
2016-2018
PHC6946 Public Health Internship
2017
PHC4930 Special Topics in Public Health
2015
PHC6900 Environmental and Global Health Journal Club
2021
HSC4913 Supervised Resrch Exp
2021
VME6934 Topics in Veterinary Medical Sciences
2021
PHC6945 Public Health Practicum
2021
PHC6917 Supervised Research Project

Contact Details

Phones:
Business:
(352) 294-4703
Emails: